
- Born:
- 4. June 1604
- Deceased:
- 25. December 1648 (from the consequences of dropsy)
- Father:
Grand Duke Ferdinand I. de' Medici of Tuscany (1549-1609)
- Mother:
Christina of Lorraine (1565-1636)
- Spouse:
- Federico Ubaldo della Rovere (1605-1623), son of Duke Francesco Maria II. della Rovere (1549-1631) of Urbino; marriage on 29. April 1621
- Leopold V. (1586-1632), Archduke of Austria-Tyrol and former Bishop of Passau and Strasbourg; marriage on 19. April 1626
- Children:
from her first marriage to Federigo della Rovere (1605-1623):
- her daughter Vittoria della Rovere, born on 7. February 1622, deceased on 5. March 1694
from her second marriage to Archduke Leopold V. (1586-1632):
- her daughter Maria Eleonora, born on 9. February 1627, deceased on 29. July 1629 (of dysentery)
- her son Ferdinand Karl, born on 17. May 1628, deceased on 30. December 1662
- her daughter Isabella Klara, born on 12. August 1629, deceased on 24. February 1685; on 7. November 1649 she became married to Duke Charles II. Gonzaga of Mantua and Montferrat (1629-1665); a son, Ferdinand Charles I. Gonzaga of Mantua und Montferrat (1652-1708), resulted from this marriage
- her son Sigismund Franz, Bishop of Augsburg (1646-1662), born on 28. November 1630, deceased on 25. June 1665; his wedding to Maria Hedwig Augusta of Sulzbach (1650-1681), daughter of Count Palatine Christian August of Sulzbach, was celebrated per procurationem on 3. June 1665; but he never saw his bride because of his death on 25. June 1665; he died of a stroke at the age of 35 or according to another historical source of high fever
- her daughter Maria Leopoldine, born on 6. April 1632, deceased on 7. August 1649 as a consequence of the very difficult birth of her only child, her son Karl Josef (1649-1664); in 1648 she had been married to her cousin Emperor Ferdinand III. (1608-1657)