24. January 1444

26. December 1476; assassinated

Francesco Sforza († 1466), Duke of Milan

Bianca Maria Visconti († 1468), daughter of the Milanese Duke Filippo Maria Visconti († 1447)

1. Dorotea Gonzaga (1450-1467), daughter of Lodovico III. Gonzaga, Margrave of Mantua († 1478)
2. Bona of Savoy (1449-1503), sister-in-law of the French King Louis XI. († 1483); marriage on 6. July 1468 (Information about the French Valois available only in German)

see: Bona of Savoy

from his relationship with Lucrezia, who became married to Giampietro Landriani:

1. his son Alessandro (c. 1460-1523), since 1474 Count of Galliate, since 1490 married to Countess Barbara Balbiani of Valchiavenna († c. 1520): one daughter: Camilla (1492-1554), who was married to Count Giulio Malvezzi († 1522/40) in 1506
2. his son Carlo (c. 1462-1483), since 1476 Count of Magenta; married to Bianca Simonetta († 1487), daughter of Count Agnolo Simonetta; two daughters: Angela and Ippolita
3. his daughter Caterina (1463-1509)
4. his daughter Chiara (1464/65-1531), her first husband was Pietro († 1485), Count dal Verme di Sanguinetto, Lord of Vigevano, they married in 1480; her second husband was Fregosino Campofregoso (1460-1512), Lord of Novi, they married in 1487 – Chiara had two sons from her second marriage: Paolo (1489-1545) and Ottaviano (1491/92-1525)

from his relationship with Lucia Marliani, who became married to Ambrogio Raverti and whom he promoted to become Countess of Melzo:

1. his son Galeazzo (1474-1515), Count of Melzo since 1493
2. his son Ottaviano (1476-1541), since 1497 Bishop of Lodi and since 1519 also Bishop of Arezzo