Francesco II. Maria Sforza, Duke of Milan of 1521-1524, 1525, 1529-1535; cousin of Isabella of Aragon, with the symbol of the "Sforza-nose"; when he was 35 years old, he was already a seriously ill man, as the following report of the Venetian Marin Sanudo, written on 11 October 1530, shows: „... The duke [Francesco II Maria Sforza] had difficulty walking -, and his ambassador, who lives here [in Venice], went along with him, giving him a hand to help him. His Excellency was followed by his [half-]brother [Gian Paolo] ... The duke usually travels on a small mule... [he is] very melancholic; he has difficulty using his hands and walks poorly." (in: Venice – Cítà Excelentissima – Selections from the Renaissance Diaries of Marin Sanudo. Edited by Patricia H. Labalme and Laura Sanguineti White. Translated by Linda L. Carroll. Baltimore 2008, pp. 78-79).
4. February 1495
31. October/1. November 1535
Lodovico Maria il Moro Sforza († 1508), Duke of Milan
Beatrice d'Este († 1497), daughter of Duke Ercole I. of Ferrara, Reggio and Modena († 1505)
Christina of Denmark (1521-1590), niece of Emperor Charles V. († 1558); marriage on 28. September 1533 (per procurationem) (information about the Hapsburgs only available in German)
none
