in the year 1478

in the year 1515

Lorenzo "il Magnifico" de' Medici (1449-1492)

Clarice Orsini (1453-1488), daughter of Jacopo Orsini of Monterotondo

Count Palatine Piero Ridolfi († 1525); marriage in the year 1493

1. her daughter Emilia, who was married to Jacopo V. Appiani d'Aragona, the ruler of Piombino
2. her son Luigi, born on 28. August 1495, deceased on 18. May 1556
3. her son Niccolò, born in the year 1501, deceased on 31. January 1550; Cardinal since 1517
4. her son Lorenzo, born on 6. September 1503, deceased on 29. September 1576; he married Maria, a daughter of Filippo Strozzi († 1538) and Clarice de' Medici († 1528), in 1529
5. bis 7.: three more children, who died shortly after birth or as infants